ALOX5AP antibody
Quick Overview for ALOX5AP antibody (ABIN7265656)
Target
See all ALOX5AP AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- FLAP Rabbit mAb
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Cross-Reactivity
- Human
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Characteristics
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- A synthesized peptide derived from human FLAP
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))
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Alternative Name
- ALOX5AP
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Background
- This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2011],FLAP,Cardiovascular,Cell Intrinsic Innate Immunity Signaling Pathway,Immunology & Inflammation,Signal Transduction,ALOX5AP
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Molecular Weight
- 16kDa
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Gene ID
- 241
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UniProt
- P20292
Target
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