ATP2B1 antibody (AA 250-350)

Catalog No. ABIN7265754

Product Details anti-ATP2B1 Antibody

Target: ATP2B1 (ATPase, Ca++ Transporting, Plasma Membrane 1 (ATP2B1))

Binding Specificity: AA 250-350

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP2B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: ATP2B1 Rabbit pAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 250-350 of human ATP2B1 (NP_001673.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ATP2B1

Target: ATP2B1 (ATPase, Ca++ Transporting, Plasma Membrane 1 (ATP2B1))

Alternative Name: ATP2B1 (ATP2B1 Products)

Synonyms: PMCA1 antibody, PMCA1kb antibody, PMCA antibody, 2810442I22Rik antibody, E130111D10Rik antibody, Pmca1 antibody, ATP2B1 antibody, DKFZp459A1127 antibody, atp2b1 antibody, Pmca1a antibody, Pmca1b antibody, Pmca1c antibody, pmca1 antibody, pmca1a antibody, sb:cb801 antibody, si:dkey-18o7.1 antibody, wu:fe47b06 antibody, wu:fi41d01 antibody, atp2b1b antibody, ATPase plasma membrane Ca2+ transporting 1 antibody, ATPase, Ca++ transporting, plasma membrane 1 antibody, plasma membrane calcium-transporting ATPase 2 antibody, ATPase, Ca++ transporting, plasma membrane 1a antibody, ATPase, Ca++ transporting, plasma membrane 1 L homeolog antibody, ATP2B1 antibody, Atp2b1 antibody, atp2b1 antibody, LOC100180580 antibody, atp2b1a antibody, atp2b1.L antibody

Background: The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],PMCA1, PMCA1kb,Calcium Signaling,Cancer,Endocrine & Metabolism,Neuroscience,Signal Transduction,ATP2B1

Gene ID: 490

UniProt: P20020

Pathways: Ribonucleoside Biosynthetic Process