ATP1A4 antibody (AA 1-90)

Catalog No. ABIN7265771

The Rabbit Polyclonal anti-ATP1A4 antibody is suitable to detect ATP1A4 in samples from Human. It has been validated for WB.

Quick Overview for ATP1A4 antibody (AA 1-90) (ABIN7265771)

Target: ATP1A4 (ATPase, Na+/K+ Transporting, alpha 4 Polypeptide (ATP1A4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP1A4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ATP1A4 Antibody

Binding Specificity: AA 1-90

Purpose: ATP1A4 Rabbit pAb

Sequence: MGLWGKKGTV APHDQSPRRR PKKGLIKKKM VKREKQKRNM EELKKEVVMD DHKLTLEELS TKYSVDLTKG HSHQRAKEIL TRGGPNTVTP

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human ATP1A4 (NP_653300.2).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ATP1A4

Target: ATP1A4 (ATPase, Na+/K+ Transporting, alpha 4 Polypeptide (ATP1A4))

Alternative Name: ATP1A4

Background: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 4 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified.,ATP1A4,ATP1A1,ATP1AL2,ATP1A4

Molecular Weight: 19kDa/114kDa

Gene ID: 480

UniProt: Q13733

Pathways: Thyroid Hormone Synthesis, Proton Transport, Ribonucleoside Biosynthetic Process