Aurora Kinase B antibody (AA 1-344)

Catalog No. ABIN7265783

The Rabbit Polyclonal anti-Aurora Kinase B antibody has been validated for IHC and WB. It is suitable to detect Aurora Kinase B in samples from Human.

Quick Overview for Aurora Kinase B antibody (AA 1-344) (ABIN7265783)

Target: Aurora Kinase B (AURKB)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aurora Kinase B antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-Aurora Kinase B Antibody

Binding Specificity: AA 1-344

Purpose: Aurora B Rabbit pAb

Sequence: MAQKENSYPW PYGRQTAPSG LSTLPQRVLR KEPVTPSALV LMSRSNVQPT AAPGQKVMEN SSGTPDILTR HFTIDDFEIG RPLGKGKFGN VYLAREKKSH FIVALKVLFK SQIEKEGVEH QLRREIEIQA HLHHPNILRL YNYFYDRRRI YLILEYAPRG ELYKELQKSC TFDEQRTATI MEELADALMY CHGKKVIHRD IKPENLLLGL KGELKIADFG WSVHAPSLRR KTMCGTLDYL PPEMIEGRMH NEKVDLWCIG VLCYELLVGN PPFESASHNE TYRRIVKVDL KFPASVPMGA QDLISKLLRH NPSERLPLAQ VSAHPWVRAN SRRVLPPSAL QSVA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-344 of human Aurora B (NP_004208.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Aurora Kinase B

Target: Aurora Kinase B (AURKB)

Alternative Name: AURKB

Background: This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Alternatively spliced transcript variants have been found for this gene.,AIK2,AIM-1,AIM1,ARK2,AurB,IPL1,PPP1R48,STK12,STK5,aurkb-sv1,aurkb-sv2,AURKB,Aurora B,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Phosphorylation,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Cell Cycle,Centromere,Microtubules,AURKB

Molecular Weight: 16kDa/34kDa/35kDa/39kDa

Gene ID: 9212

UniProt: Q96GD4

Pathways: TCR Signaling, Cell Division Cycle, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades