BAG2 antibody

Catalog No. ABIN7265849

The Rabbit Monoclonal anti-BAG2 antibody has been validated for WB and IHC. It is suitable to detect BAG2 in samples from Human.

Quick Overview for BAG2 antibody (ABIN7265849)

Target: BAG2 (BCL2-Associated Athanogene 2 (BAG2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This BAG2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-BAG2 Antibody

Purpose: BAG2 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human BAG2

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BAG2

Target: BAG2 (BCL2-Associated Athanogene 2 (BAG2))

Alternative Name: BAG2

Background: BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008],BAG-2, dJ417I1.2,Apoptosis,Apoptosis_Bcl 2 family,Cancer,Cell Biology & Developmental Biology,Endocrine & Metabolism,Invasion and Metastasis,Signal Transduction,BAG2

Molecular Weight: 24kDa

Gene ID: 9532

UniProt: O95816