Beclin 1 antibody (pSer90)

Catalog No. ABIN7265872

This Rabbit Polyclonal antibody specifically detects Beclin 1 in WB. It exhibits reactivity toward Human.

Quick Overview for Beclin 1 antibody (pSer90) (ABIN7265872)

Target: Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Beclin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Beclin 1 Antibody

Binding Specificity: pSer90

Purpose: Phospho-Beclin 1-Ser90 Rabbit pAb

Cross-Reactivity: Human, Mouse

Characteristics: Phosphorylated Antibodies

Purification: Affinity purification

Immunogen: A phospho specific peptide corresponding to residues surrounding Ser90 of human Beclin 1

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Beclin 1

Target: Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

Alternative Name: BECN1

Background: This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.,ATG6,VPS30,beclin1,Beclin 1,BECN1,beclin-1,Apoptosis,Autophagy,Autophagy_Regulator,Cancer,Cell Biology & Developmental Biology,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,Mitochondrial metabolism,Signal Transduction,Tumor suppressors,BECN1

Molecular Weight: 52kDa

Gene ID: 8678

UniProt: Q14457

Pathways: Autophagy