BMX
Reactivity: Human
ELISA
Host: Mouse
Monoclonal
1C6
unconjugated
Application Notes
WB,1:500 - 1:2000
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target
BMX
(BMX Non-Receptor Tyrosine Kinase (BMX))
Alternative Name
BMX
Background
This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene.,BMX,ETK,PSCTK2,PSCTK3,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Apoptosis,Wnt/β-Catenin Signaling Pathway,BMX