BRD4
Reactivity: Human
IHC (p)
Host: Rabbit
Polyclonal
RB3419
unconjugated
Application Notes
WB,1:500 - 1:2000
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target
BRD4
(Bromodomain Containing 4 (BRD4))
Alternative Name
BRD4
Background
The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15,19)(q13,p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008],BRD4, CAP, HUNK1, HUNKI, MCAP, bromodomain containing 4,Cancer,Epigenetics & Nuclear Signaling,Kinase,Kinase_Serine/threonine kinases,Signal Transduction,Tumor suppressors,BRD4