CTNNA2 antibody (AA 150-300)
Quick Overview for CTNNA2 antibody (AA 150-300) (ABIN7266134)
Target
See all CTNNA2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 150-300
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Purpose
- CTNNA2 Rabbit pAb
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Sequence
- LSHLKIVEEA LEAVKNATNE QDLANRFKEF GKEMVKLNYV AARRQQELKD PHCRDEMAAA RGALKKNATM LYTASQAFLR HPDVAATRAN RDYVFKQVQE AIAGISNAAQ ATSPTDEAKG HTGIGELAAA LNEFDNKIIL DPMTFSEARF R
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 150-300 of human CTNNA2 (NP_004380.2).
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Isotype
- IgG
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Application Notes
- WB,1:200 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- CTNNA2 (Catenin (Cadherin-Associated Protein), alpha 2 (CTNNA2))
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Alternative Name
- CTNNA2
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Background
- May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system (By similarity. Required for proper regulation of cortical neuronal migration and neurite growth. It acts as negative regulator of Arp2/3 complex activity and Arp2/3-mediated actin polymerization. It thereby suppresses excessive actin branching which would impair neurite growth and stability. Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Functions in the control of startle modulation (By similarity.,CTNNA2,CAP-R,CAPR,CT114,CTNR,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cadherins,Cytoskeleton,Wnt/β-Catenin Signaling Pathway,CTNNA2
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Molecular Weight
- 59kDa/65kDa/95kDa/100kDa/104kDa/105kDa
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Gene ID
- 1496
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UniProt
- P26232
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Pathways
- Regulation of Muscle Cell Differentiation
Target
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