CDK1/2/3 (pThr14) antibody

Catalog No. ABIN7266234

The Rabbit Monoclonal anti-CDK1/2/3 antibody (ABIN7266234) specifically detects CDK1/2/3 in WB. The antibody is reactive with Human samples.

Quick Overview for CDK1/2/3 (pThr14) antibody (ABIN7266234)

Target: CDK1/2/3

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: pThr14

Purpose: Phospho-CDK1/2/3-T14 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Phosphorylated Antibodies

Purification: Affinity purification

Immunogen: A phospho specific peptide corresponding to residues surrounding T14 of human CDK1/2/3

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details

Target: CDK1/2/3

Alternative Name: CDK1/CDK2/CDK3

Background: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],CDC2, CDC28A, P34CDC2,Apoptosis,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Centrosome,Cytoskeleton_Microtubules,Epigenetics & Nuclear Signaling,ErbB-HER Signaling Pathway,G protein signaling,G2/M DNA Damage Checkpoint,Immunology & Inflammation,Kinase,Kinase_Serine/threonine kinases,Neurodegenerative Diseases,Neuroscience,Protein phosphorylation,Signal Transduction,CDK1/CDK2/CDK3

Molecular Weight: 34kDa

Gene ID: 983, 1017, 1018

UniProt: P06493, P24941, Q00526