CDS2 antibody (AA 1-100)

Catalog No. ABIN7266239

The Rabbit Polyclonal anti-CDS2 antibody is suitable to detect CDS2 in samples from Human. It has been validated for WB and IHC.

Quick Overview for CDS2 antibody (AA 1-100) (ABIN7266239)

Target: CDS2 (CDP-Diacylglycerol Synthase (Phosphatidate Cytidylyltransferase) 2 (CDS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CDS2 Antibody

Binding Specificity: AA 1-100

Purpose: CDS2 Rabbit pAb

Sequence: MTELRQRVAH EPVAPPEDKE SESEAKVDGE TASDSESRAE SAPLPVSADD TPEVLNRALS NLSSRWKNWW VRGILTLAMI AFFFIIIYLG PMVLMIIVMC

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CDS2 (NP_003809.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CDS2

Target: CDS2 (CDP-Diacylglycerol Synthase (Phosphatidate Cytidylyltransferase) 2 (CDS2))

Alternative Name: CDS2

Background: Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13.,CDS2,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Lipid Metabolism,CDS2

Molecular Weight: 29kDa/51kDa

Gene ID: 8760

UniProt: O95674