CDC23 antibody (AA 50-150)

Catalog No. ABIN7266248

The Rabbit Polyclonal anti-CDC23 antibody has been validated for WB and IHC. It is suitable to detect CDC23 in samples from Human.

Quick Overview for CDC23 antibody (AA 50-150) (ABIN7266248)

Target: CDC23 (Cell Division Cycle 23 (CDC23))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC23 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CDC23 Antibody

Binding Specificity: AA 50-150

Purpose: CDC23 Rabbit pAb

Sequence: HSSKWSAELA FSLPALPLAE LQPPPPITEE DAQDMDAYTL AKAYFDVKEY DRAAHFLHGC NSKKAYFLYM YSRYLSGEKK KDDETVDSLG PLEKGQVKNE A

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human CDC23 (NP_004652.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CDC23

Target: CDC23 (Cell Division Cycle 23 (CDC23))

Alternative Name: CDC23

Background: The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.,CDC23,ANAPC8,APC8,CUT23,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cyclins,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,CDC23

Molecular Weight: 16kDa/55kDa/68kDa

Gene ID: 8697

UniProt: Q9UJX2

Pathways: Protein targeting to Nucleus