CHAC1 antibody (AA 45-264)

Catalog No. ABIN7266287

The Rabbit Polyclonal anti-CHAC1 antibody has been validated for WB. It is suitable to detect CHAC1 in samples from Human.

Quick Overview for CHAC1 antibody (AA 45-264) (ABIN7266287)

Target: CHAC1 (ChaC, Cation Transport Regulator Homolog 1 (CHAC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHAC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHAC1 Antibody

Binding Specificity: AA 45-264

Purpose: CHAC1 Rabbit pAb

Sequence: QESAAPNTPP TSQSPTPSAQ FPRNDGDPQA LWIFGYGSLV WRPDFAYSDS RVGFVRGYSR RFWQGDTFHR GSDKMPGRVV TLLEDHEGCT WGVAYQVQGE QVSKALKYLN VREAVLGGYD TKEVTFYPQD APDQPLKALA YVATPQNPGY LGPAPEEAIA TQILACRGFS GHNLEYLLRL ADFMQLCGPQ AQDEHLAAIV DAVGTMLPCF CPTEQALALV

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 45-264 of human CHAC1 (NP_077016.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CHAC1

Target: CHAC1 (ChaC, Cation Transport Regulator Homolog 1 (CHAC1))

Alternative Name: CHAC1

Background: This gene encodes a member of the gamma-glutamylcyclotransferase family of proteins. The encoded protein has been shown to promote neuronal differentiation by deglycination of the Notch receptor, which prevents receptor maturation and inhibits Notch signaling. This protein may also play a role in the unfolded protein response, and in regulation of glutathione levels and oxidative balance in the cell. Elevated expression of this gene may indicate increased risk of cancer recurrence among breast and ovarian cancer patients. [provided by RefSeq, Sep 2016],CHAC1,Cell Biology & Developmental Biology,Apoptosis,CHAC1

Molecular Weight: 23kDa/28kDa

Gene ID: 79094

UniProt: Q9BUX1