CXCR1 antibody (AA 250-350)

Catalog No. ABIN7266317

The Rabbit Polyclonal anti-CXCR1 antibody has been validated for WB and IHC. It is suitable to detect CXCR1 in samples from Human.

Quick Overview for CXCR1 antibody (AA 250-350) (ABIN7266317)

Target: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CXCR1 Antibody

Binding Specificity: AA 250-350

Purpose: CXCR1 Rabbit pAb

Sequence: IFLLCWLPYN LVLLADTLMR TQVIQESCER RNNIGRALDA TEILGFLHSC LNPIIYAFIG QNFRHGFLKI LAMHGLVSKE FLARHRVTSY TSSSVNVSSN L

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CXCR1 (NP_000625.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CXCR1

Target: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Alternative Name: CXCR1

Background: The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.,CXCR1,C-C,C-C-CKR-1,CD128,CD181,CDw128a,CKR-1,CMKAR1,IL8R1,IL8RA,IL8RBA,Cancer,Tumor immunology,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Immunology & Inflammation,CD markers,Cytokines,Cell Intrinsic Innate Immunity Signaling Pathway,Chemokines,Chemokine,CXCR1

Molecular Weight: 39kDa

Gene ID: 3577

UniProt: P25024

Pathways: cAMP Metabolic Process