CXCR4 antibody

Catalog No. ABIN7266319

This Rabbit Monoclonal antibody specifically detects CXCR4 in WB. It exhibits reactivity toward Human.

Quick Overview for CXCR4 antibody (ABIN7266319)

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CXCR4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CXCR4 Antibody

Purpose: CXCR4 Rabbit mAb

Cross-Reactivity: Human

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human CXCR4

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CXCR4

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Alternative Name: CXCR4

Background: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],CD184,D2S201E,FB22,HM89,HSY3RR,LAP-3,LAP3,LCR1,LESTR,NPY3R,NPYR,NPYRL,NPYY3R,WHIM,WHIMS,CXCR4,Angiogenesis,Apoptosis,Cancer,Cardiovascular,CDs,Cell Biology & Developmental Biology,Cell Intrinsic Innate Immunity Signaling Pathway,Endocrine & Metabolism,Endothelial Progenitors,ErbB-HER Signaling Pathway,G protein signaling,G protein signaling_G-Protein-Coupled Receptors(GPCR),Hematopoietic Progenitors,Immunology & Inflammation,Innate Immunity_Chemokines,Neural Stem Cells,Neuroscience,Signal Transduction,Stem Cells,CXCR4

Molecular Weight: 43kDa

Gene ID: 7852

UniProt: P61073

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events