Claudin 17 antibody (C-Term)

Catalog No. ABIN7266407

The Rabbit Polyclonal anti-Claudin 17 antibody has been validated for WB, IHC and IF. It is suitable to detect Claudin 17 in samples from Human.

Quick Overview for Claudin 17 antibody (C-Term) (ABIN7266407)

Target: Claudin 17 (CLDN17)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 17 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Claudin 17 Antibody

Binding Specificity: C-Term

Purpose: CLDN17 Rabbit pAb

Sequence: CGMKQVQCTG SNERAKAYLL GTSGVLFILT GIFVLIPVSW TANIIIRDFY NPAIHIGQKR ELGAALFLGW ASAAVLFIGG GLLCGFCCCN RKKQGYRYPV PGYRVPHTDK RRNTTMLSKT STSYV

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human CLDN17 (NP_036263.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Claudin 17

Target: Claudin 17 (CLDN17)

Alternative Name: CLDN17

Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and is clustered with CLDN8 on chromosome 21q22.11.,CLDN17,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,Cytoskeleton,CLDN17

Molecular Weight: 24kDa

Gene ID: 26285

UniProt: P56750

Pathways: Cell-Cell Junction Organization, Hepatitis C