Coronavirus Spike Glycoprotein antibody

Catalog No. ABIN7266506

The Rabbit Polyclonal anti-Coronavirus Spike Glycoprotein antibody is suitable to detect Coronavirus Spike Glycoprotein in samples from SARS Coronavirus-2 (SARS-CoV-2). It has been validated for ELISA, WB, IP and IF.

Quick Overview for Coronavirus Spike Glycoprotein antibody (ABIN7266506)

Target: Coronavirus Spike Glycoprotein (CoV S)

Reactivity: SARS Coronavirus-2 (SARS-CoV-2)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Coronavirus Spike Glycoprotein antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)

Product Details anti-Coronavirus Spike Glycoprotein Antibody

Purpose: SARS-CoV-2 Spike Rabbit pAb

Cross-Reactivity: SARS Coronavirus-2 (SARS-CoV-2)

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide of SARS-CoV-2 Spike.

Isotype: IgG

Application Details

Application Notes: ELISA,1:40000-1:160000,WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Coronavirus Spike Glycoprotein

Target: Coronavirus Spike Glycoprotein (CoV S)

Alternative Name: Spike

Target Type: Viral Protein

Background: The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. The spike is essential for both host specificity and viral infectivity. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. It''s been reported that SARS-CoV-2 (COVID-19 coronavirus, 2019-nCoV) can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. The main functions for the Spike protein are summarized as: Mediate receptor binding and membrane fusion, Defines the range of the hosts and specificity of the virus, Main component to bind with the neutralizing antibody, Key target for vaccine design, Can be transmitted between different hosts through gene recombination or mutation of the receptor binding domain (RBD), leading to a higher mortality rate.,Spike

Gene ID: 43740568

UniProt: P0DTC2