D2HGDH antibody (AA 322-521)

Catalog No. ABIN7266669

The Rabbit Polyclonal anti-D2HGDH antibody (ABIN7266669) specifically detects D2HGDH in WB. The antibody is reactive with Human samples.

Quick Overview for D2HGDH antibody (AA 322-521) (ABIN7266669)

Target: D2HGDH (D-2-Hydroxyglutarate Dehydrogenase (D2HGDH))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This D2HGDH antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-D2HGDH Antibody

Binding Specificity: AA 322-521

Purpose: D2HGDH Rabbit pAb

Sequence: GRHLHLASPV QESPFYVLIE TSGSNAGHDA EKLGHFLEHA LGSGLVTDGT MATDQRKVKM LWALRERITE ALSRDGYVYK YDLSLPVERL YDIVTDLRAR LGPHAKHVVG YGHLGDGNLH LNVTAEAFSP SLLAALEPHV YEWTAGQQGS VSAEHGVGFR KRDVLGYSKP PGALQLMQQL KALLDPKGIL NPYKTLPSQA

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 322-521 of human D2HGDH (NP_689996.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for D2HGDH

Target: D2HGDH (D-2-Hydroxyglutarate Dehydrogenase (D2HGDH))

Alternative Name: D2HGDH

Background: This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features.,D2HGDH,D2HGD,Signal Transduction,Endocrine & Metabolism,D2HGDH

Molecular Weight: 32kDa/34kDa/56kDa

Gene ID: 728294

UniProt: Q8N465