Dynamin 1-Like antibody (pSer616)

Catalog No. ABIN7266857

The Rabbit Polyclonal anti-Dynamin 1-Like antibody has been validated for WB. It is suitable to detect Dynamin 1-Like in samples from Human.

Quick Overview for Dynamin 1-Like antibody (pSer616) (ABIN7266857)

Target: Dynamin 1-Like (DNM1L)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dynamin 1-Like antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Dynamin 1-Like Antibody

Binding Specificity: pSer616

Purpose: Phospho-DRP1-S616 Rabbit pAb

Sequence: PASPQ

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Phosphorylated Antibodies

Purification: Affinity purification

Immunogen: A synthetic phosphorylated peptide around S616 of human DRP1 (NP_036192.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Dynamin 1-Like

Target: Dynamin 1-Like (DNM1L)

Alternative Name: DNM1L

Background: This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.,DNM1L,DLP1,DRP1,DVLP,DYMPLE,EMPF,EMPF1,HDYNIV,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,Protein phosphorylation,DNM1L

Molecular Weight: 60kDa/78kDa/79kDa/80kDa/81kDa/82kDa/83kDa

Gene ID: 10059

UniProt: O00429