RAD18 antibody

Catalog No. ABIN7266884

The Rabbit Monoclonal anti-RAD18 antibody is suitable to detect RAD18 in samples from Human. It has been validated for WB.

Quick Overview for RAD18 antibody (ABIN7266884)

Target: RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This RAD18 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RAD18 Antibody

Purpose: Rad18 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Rad18

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RAD18

Target: RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))

Alternative Name: RAD18

Background: The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq, Jul 2008],RNF73,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,Ubiquitin,RAD18

Molecular Weight: 56kDa

Gene ID: 56852

UniProt: Q9NS91