EDARADD antibody (AA 1-215)

Catalog No. ABIN7266900

The Rabbit Polyclonal anti-EDARADD antibody (ABIN7266900) specifically detects EDARADD in WB. The antibody is reactive with Human samples.

Quick Overview for EDARADD antibody (AA 1-215) (ABIN7266900)

Target: EDARADD (EDAR-Associated Death Domain (EDARADD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EDARADD antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EDARADD Antibody

Binding Specificity: AA 1-215

Purpose: EDARADD Rabbit pAb

Sequence: MGLRTTKQMG RGTKAPGHQE DHMVKEPVED TDPSTLSFNM SDKYPIQDTE LPKAEECDTI TLNCPRNSDM KNQGEENGFP DSTGDPLPEI SKDNSCKENC TCSSCLLRAP TISDLLNDQD LLDVIRIKLD PCHPTVKNWR NFASKWGMSY DELCFLEQRP QSPTLEFLLR NSQRTVGQLM ELCRLYHRAD VEKVLRRWVD EEWPKRERGD PSRHF

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-215 of human EDARADD (NP_665860.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EDARADD

Target: EDARADD (EDAR-Associated Death Domain (EDARADD))

Alternative Name: EDARADD

Background: This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.,EDARADD,ECTD11A,ECTD11B,ED3,EDA3,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,EDARADD

Molecular Weight: 23kDa/24kDa

Gene ID: 128178

UniProt: Q8WWZ3

Pathways: Ubiquitin Proteasome Pathway