ELL antibody (AA 350-450)
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- Target See all ELL Antibodies
- ELL (Elongation Factor RNA Polymerase II (ELL))
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Binding Specificity
- AA 350-450
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ELL antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purpose
- ELL Rabbit pAb
- Sequence
- PAVNGKLGVP NGREALLPTP GPPASTDTLS SSTHLPPRLE PPRAHDPLAD VSNDLGHSGR DCEHGEAAAP APTVRLGLPL LTDCAQPSRP HGSPSRSKPK K
- Cross-Reactivity
- Mouse
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 350-450 of human ELL (NP_006523.1).
- Isotype
- IgG
- Top Product
- Discover our top product ELL Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ELL (Elongation Factor RNA Polymerase II (ELL))
- Alternative Name
- ELL (ELL Products)
- Background
- Elongation factor component of the super elongation complex (SEC, a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Elongation factor component of the little elongation complex (LEC, a complex required to regulate small nuclear RNA (snRNA gene transcription by RNA polymerase II and III. Specifically required for stimulating the elongation step of RNA polymerase II- and III-dependent snRNA gene transcription. ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation.,ELL,C19orf17,ELL1,MEN,PPP1R68,Epigenetics & Nuclear Signaling,Cancer,ELL
- Molecular Weight
- 68kDa
- Gene ID
- 8178
- UniProt
- P55199
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