ERAP1 antibody

Catalog No. ABIN7266941

The Rabbit Monoclonal anti-ERAP1 antibody is suitable to detect ERAP1 in samples from Human. It has been validated for WB and IHC.

Quick Overview for ERAP1 antibody (ABIN7266941)

Target: ERAP1 (Endoplasmic Reticulum Aminopeptidase 1 (ERAP1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ERAP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ERAP1 Antibody

Purpose: ERAP1 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human ERAP1

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ERAP1

Target: ERAP1 (Endoplasmic Reticulum Aminopeptidase 1 (ERAP1))

Alternative Name: ERAP1

Background: The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene.[provided by RefSeq, Oct 2010],A-LAP, ALAP, APPILS, ARTS-1, ARTS1, ERAAP, ERAAP1, PILS-AP, PILSAP,Angiogenesis,Blood,Blood_Blood Pressure regulation,Cardiovascular,Cell Biology & Developmental Biology,Cytokines,Growth factors,Immunology & Inflammation,Ubiquitin,ERAP1

Molecular Weight: 100kDa

Gene ID: 51752

UniProt: Q9NZ08