ERLIN2 antibody

Catalog No. ABIN7267006

This Rabbit Monoclonal antibody specifically detects ERLIN2 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for ERLIN2 antibody (ABIN7267006)

Target: ERLIN2 (ER Lipid Raft Associated 2 (ERLIN2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ERLIN2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ERLIN2 Antibody

Purpose: Erlin-2 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Erlin-2.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ERLIN2

Target: ERLIN2 (ER Lipid Raft Associated 2 (ERLIN2))

Alternative Name: Erlin-2

Background: This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,ERLIN2, C8orf2, Erlin-2, NET32, SPFH2, SPG18, erlin-2,Signal Transduction,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Dopamine Signaling in Parkinson's Disease,Erlin-2

Molecular Weight: 38kDa

Gene ID: 11160

UniProt: O94905