FGFR1OP antibody (AA 1-70)

Catalog No. ABIN7267172

The Rabbit Polyclonal anti-FGFR1OP antibody has been validated for WB. It is suitable to detect FGFR1OP in samples from Human.

Quick Overview for FGFR1OP antibody (AA 1-70) (ABIN7267172)

Target: FGFR1OP (FGFR1 Oncogene Partner (FGFR1OP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGFR1OP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FGFR1OP Antibody

Binding Specificity: AA 1-70

Purpose: FGFR1OP Rabbit pAb

Sequence: MAATAAAVVA EEDTELRDLL VQTLENSGVL NRIKAELRAA VFLALEEQEK VENKTPLVNE SLKKFLNTKD

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human FGFR1OP (NP_919410.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FGFR1OP

Target: FGFR1OP (FGFR1 Oncogene Partner (FGFR1OP))

Alternative Name: FGFR1OP

Background: This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq, Jul 2013],FGFR1OP;FOP,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Growth factor,FGFR1OP

Molecular Weight: 16kDa/40kDa/43kDa

Gene ID: 11116

UniProt: O95684

Pathways: M Phase, Maintenance of Protein Location, SARS-CoV-2 Protein Interactome