FN3KRP
Reactivity: Human
Host: Rabbit
Polyclonal
Alexa Fluor 680
Application Notes
WB,1:200 - 1:2000
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target
FN3KRP
(Fructosamine 3 Kinase Related Protein (FN3KRP))
Alternative Name
FN3KRP
Background
A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of psicosamines and ribulosamines compared to the neighboring gene which encodes a highly similar enzyme, fructosamine-3-kinase, which has different substrate specificity. The activity of both enzymes may result in deglycation of proteins to restore their function. Alternative splicing results in multiple transcript variants.,FN3KRP,FN3KL,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,FN3KRP