FGD1 antibody (AA 700-800)

Catalog No. ABIN7267284

The Rabbit Polyclonal anti-FGD1 antibody (ABIN7267284) specifically detects FGD1 in WB, IHC and IF. The antibody is reactive with Human samples.

Quick Overview for FGD1 antibody (AA 700-800) (ABIN7267284)

Target: FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-FGD1 Antibody

Binding Specificity: AA 700-800

Purpose: FGD1 Rabbit pAb

Sequence: LLNSTNREDE DTPPNSPNVD LGKRAPTPIR EKEVTMCMRC QEPFNSITKR RHHCKACGHV VCGKCSEFRA RLVYDNNRSN RVCTDCYVAL HGVPGSSPAC S

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 700-800 of human FGD1 (NP_004454.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FGD1

Target: FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))

Alternative Name: FGD1

Background: This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16.,FGD1,AAS,FGDY,MRXS16,ZFYVE3,FYVE,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,FGD1

Molecular Weight: 106kDa

Gene ID: 2245

UniProt: P98174

Pathways: Neurotrophin Signaling Pathway