GEMIN5 antibody (AA 750-950)

Catalog No. ABIN7267367

The Rabbit Polyclonal anti-GEMIN5 antibody is suitable to detect GEMIN5 in samples from Human. It has been validated for WB and IHC.

Quick Overview for GEMIN5 antibody (AA 750-950) (ABIN7267367)

Target: GEMIN5 (Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GEMIN5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GEMIN5 Antibody

Binding Specificity: AA 750-950

Purpose: GEMIN5 Rabbit pAb

Sequence: RTPVKLESID GNEEESMKEN SGPVENGVSD QEGEEQAREP ELPCGLAPAV SREPVICTPV SSGFEKSKVT INNKVILLKK EPPKEKPETL IKKRKARSLL PLSTSLDHRS KEELHQDCLV LATAKHSREL NEDVSADVEE RFHLGLFTDR ATLYRMIDIE GKGHLENGHP ELFHQLMLWK GDLKGVLQTA AERGELTDNL V

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 750-950 of human GEMIN5 (NP_056280.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GEMIN5

Target: GEMIN5 (Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))

Alternative Name: GEMIN5

Background: This gene encodes a WD repeat protein that is a component of the survival of motor neurons (SMN) complex. The SMN complex plays a critical role in mRNA splicing through the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs), and may also mediate the assembly and transport of other classes of ribonucleoproteins. The encoded protein is the snRNA-binding component of the SMN complex. Dysregulation of this gene may play a role in alternative mRNA splicing and tumor cell motility. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,GEMIN5,GEMIN-5,Epigenetics & Nuclear Signaling,RNA Binding,GEMIN5

Molecular Weight: 168kDa

Gene ID: 25929

UniProt: Q8TEQ6

Pathways: Ribonucleoprotein Complex Subunit Organization