GLI3 antibody (AA 800-900)

Catalog No. ABIN7267386

The Rabbit Polyclonal anti-GLI3 antibody (ABIN7267386) specifically detects GLI3 in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for GLI3 antibody (AA 800-900) (ABIN7267386)

Target: GLI3 (GLI Family Zinc Finger 3 (GLI3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLI3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GLI3 Antibody

Binding Specificity: AA 800-900

Purpose: GLI3 Rabbit pAb

Sequence: KAPAVSPLIG NGTQSNNTCS LGGPMTLLPG RSDLSGVDVT MLNMLNRRDS SASTISSAYL SSRRSSGISP CFSSRRSSEA SQAEGRPQNV SVADSYDPIS T

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 800-900 of human GLI3 (NP_000159.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GLI3

Target: GLI3 (GLI Family Zinc Finger 3 (GLI3))

Alternative Name: GLI3

Background: This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B.,GLI3,ACLS,GCPS,GLI3-190,GLI3FL,PAP-A,PAPA,PAPA1,PAPB,PHS,PPDIV,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Cell Biology & Developmental Biology,Hedgehog Signaling Pathway,Neuroscience,Stem Cells,GLI3

Molecular Weight: 169kDa

Gene ID: 2737

UniProt: P10071

Pathways: Hedgehog Signaling