GSTM5 antibody (C-Term)

Catalog No. ABIN7267445

The Rabbit Polyclonal anti-GSTM5 antibody has been validated for WB and IF. It is suitable to detect GSTM5 in samples from Human.

Quick Overview for GSTM5 antibody (C-Term) (ABIN7267445)

Target: GSTM5 (Glutathione S-Transferase mu 5 (GSTM5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSTM5 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-GSTM5 Antibody

Binding Specificity: C-Term

Purpose: GSTM5 Rabbit pAb

Sequence: LENQVMDNHM ELVRLCYDPD FEKLKPKYLE ELPEKLKLYS EFLGKRPWFA GDKITFVDFL AYDVLDMKRI FEPKCLDAFL NLKDFISRFE GLKKISAYMK SSQFLRGLLF GKSATWNSK

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human GSTM5 (NP_000842.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GSTM5

Target: GSTM5 (Glutathione S-Transferase mu 5 (GSTM5))

Alternative Name: GSTM5

Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds.,GSTM5,GSTM5-5,GTM5,Signal Transduction,Endocrine & Metabolism,Drug metabolism,GSTM5

Molecular Weight: 25kDa

Gene ID: 2949

UniProt: P46439