Glutathione Synthetase antibody (AA 373-474)

Catalog No. ABIN7267451

The Rabbit Polyclonal anti-Glutathione Synthetase antibody is suitable to detect Glutathione Synthetase in samples from Human. It has been validated for WB and IF.

Quick Overview for Glutathione Synthetase antibody (AA 373-474) (ABIN7267451)

Target: Glutathione Synthetase (GSS)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutathione Synthetase antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Grade: KO Validated

Product Details anti-Glutathione Synthetase Antibody

Binding Specificity: AA 373-474

Purpose: [KO Validated] Glutathione Synthetase (GSS) Rabbit pAb

Sequence: NLYGEEMVQA LKQLKDSEER ASYILMEKIE PEPFENCLLR PGSPARVVQC ISELGIFGVY VRQEKTLVMN KHVGHLLRTK AIEHADGGVA AGVAVLDNPY PV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 373-474 of human Glutathione Synthetase (Glutathione Synthetase (GSS)) (NP_000169.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Glutathione Synthetase

Target: Glutathione Synthetase (GSS)

Alternative Name: GSS

Background: Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.,GSS,GSHS,HEL-S-64p,HEL-S-88n,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Amino acid metabolism,Drug metabolism,Neuroscience,GSS

Molecular Weight: 40kDa/52kDa

Gene ID: 2937

UniProt: P48637

Pathways: Warburg Effect