HEY2 antibody (AA 1-100)

Catalog No. ABIN7267562

The Rabbit Polyclonal anti-HEY2 antibody has been validated for WB. It is suitable to detect HEY2 in samples from Human.

Quick Overview for HEY2 antibody (AA 1-100) (ABIN7267562)

Target: HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HEY2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HEY2 Antibody

Binding Specificity: AA 1-100

Purpose: HEY2 Rabbit pAb

Sequence: MKRPCEETTS ESDMDETIDV GSENNYSGQS TSSVIRLNSP TTTSQIMARK KRRGIIEKRR RDRINNSLSE LRRLVPTAFE KQGSAKLEKA EILQMTVDHL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HEY2 (NP_036391.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HEY2

Target: HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))

Alternative Name: HEY2

Background: This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.,HEY2,CHF1,GRIDLOCK,GRL,HERP1,HESR2,HRT2,bHLHb32,Epigenetics & Nuclear Signaling,Transcription Factors,Stem Cells,Cardiovascular,Heart,Cardiogenesis,HEY2

Molecular Weight: 35kDa

Gene ID: 23493

UniProt: Q9UBP5

Pathways: Regulation of Muscle Cell Differentiation