HSPB11 antibody

Catalog No. ABIN7267591

This Rabbit Polyclonal antibody specifically detects HSPB11 in WB, IF and IHC. It exhibits reactivity toward Human.

Quick Overview for HSPB11 antibody (ABIN7267591)

Target: HSPB11 (Heat Shock Protein Family B (Small), Member 11 (HSPB11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSPB11 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-HSPB11 Antibody

Purpose: HSPB11 Rabbit pAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant protein of human HSPB11.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HSPB11

Target: HSPB11 (Heat Shock Protein Family B (Small), Member 11 (HSPB11))

Alternative Name: HSPB11

Background: Component of the IFT complex B required for sonic hedgehog/SHH signaling. May mediate transport of SHH components: required for the export of SMO and PTCH1 receptors out of the cilium and the accumulation of GLI2 at the ciliary tip in response to activation of the SHH pathway, suggesting it is involved in the dynamic transport of SHH signaling molecules within the cilium. Not required for ciliary assembly. Its role in intraflagellar transport is mainly seen in tissues rich in ciliated cells such as kidney and testis. Essential for male fertility, spermiogenesis and sperm flagella formation. Plays a role in the early development of the kidney. May be involved in the regulation of ureteric bud initiation (By similarity.,HSPB11,C1orf41,HSPCO34,IFT25,PP25,HSPB11

Molecular Weight: 16kDa

Gene ID: 51668

UniProt: Q9Y547