HDAC8 antibody

Catalog No. ABIN7267714

This Rabbit Monoclonal antibody specifically detects HDAC8 in WB, IHC, IF and IP. It exhibits reactivity toward Human.

Quick Overview for HDAC8 antibody (ABIN7267714)

Target: HDAC8 (Histone Deacetylase 8 (HDAC8))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This HDAC8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Grade: KO Validated

Product Details anti-HDAC8 Antibody

Purpose: [KO Validated] HDAC8 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human HDAC8

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HDAC8

Target: HDAC8 (Histone Deacetylase 8 (HDAC8))

Alternative Name: HDAC8

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],CDA07, CDLS5, HD8, HDACL1, MRXS6, RPD3, WTS,Cardiovascular,Epigenetics & Nuclear Signaling,Heart,Heart_Hypertrophy,Immunology & Inflammation,NF-kB Signaling Pathway,Nuclear Receptor Signaling,Stem Cells,HDAC8

Molecular Weight: 42kDa

Gene ID: 55869

UniProt: Q9BY41

Pathways: Cellular Glucan Metabolic Process