HTRA3 antibody (AA 334-453)

Catalog No. ABIN7267790

The Rabbit Polyclonal anti-HTRA3 antibody is suitable to detect HTRA3 in samples from Human. It has been validated for WB and IHC.

Quick Overview for HTRA3 antibody (AA 334-453) (ABIN7267790)

Target: HTRA3 (HtrA Serine Peptidase 3 (HTRA3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HTRA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-HTRA3 Antibody

Binding Specificity: AA 334-453

Purpose: HTRA3 Rabbit pAb

Sequence: SDRITRFLTE FQDKQIKDWK KRFIGIRMRT ITPSLVDELK ASNPDFPEVS SGIYVQEVAP NSPSQRGGIQ DGDIIVKVNG RPLVDSSELQ EAVLTESPLL LEVRRGNDDL LFSIAPEVVM

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 334-453 of human HTRA3 (NP_444272.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HTRA3

Target: HTRA3 (HtrA Serine Peptidase 3 (HTRA3))

Alternative Name: HTRA3

Background: Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans (By similarity. May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization.,HTRA3,Prsp,Tasp,Signal Transduction,Neuroscience,Calcium Signaling,HTRA3

Molecular Weight: 37kDa/48kDa

Gene ID: 94031

UniProt: P83110