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INPP5E antibody (AA 510-630)

INPP5E Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7267883
  • Target See all INPP5E Antibodies
    INPP5E (Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E))
    Binding Specificity
    • 4
    • 3
    • 2
    AA 510-630
    Reactivity
    • 18
    • 10
    • 10
    Human
    Host
    • 16
    • 2
    Rabbit
    Clonality
    • 18
    Polyclonal
    Conjugate
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This INPP5E antibody is un-conjugated
    Application
    • 7
    • 6
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Purpose
    INPP5E Rabbit pAb
    Sequence
    LIREMRKGSI FKGFQEPDIH FLPSYKFDIG KDTYDSTSKQ RTPSYTDRVL YRSRHKGDIC PVSYSSCPGI KTSDHRPVYG LFRVKVRPGR DNIPLAAGKF DRELYLLGIK RRISKEIQRQ Q
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 510-630 of human INPP5E (NP_063945.2).
    Isotype
    IgG
    Top Product
    Discover our top product INPP5E Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    INPP5E (Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E))
    Alternative Name
    INPP5E (INPP5E Products)
    Synonyms
    1200002L24Rik antibody, 72kDa antibody, mKIAA0123 antibody, CORS1 antibody, CPD4 antibody, JBTS1 antibody, MORMS antibody, PPI5PIV antibody, PMPCA antibody, inositol polyphosphate-5-phosphatase E antibody, Inpp5e antibody, INPP5E antibody
    Background
    The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. Studies of the mouse counterpart suggest that this protein may hydrolyze phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,5-bisphosphate on the cytoplasmic Golgi membrane and thereby regulate Golgi-vesicular trafficking. Mutations in this gene cause Joubert syndrome, a clinically and genetically heterogenous group of disorders characterized by midbrain-hindbrain malformation and various associated ciliopathies that include retinal dystrophy, nephronophthisis, liver fibrosis and polydactyly. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],CORS1,CPD4,JBTS1,MORMS,PPI5PIV,pharbin,INPP5E,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,INPP5E
    Molecular Weight
    66kDa/70kDa
    Gene ID
    56623
    UniProt
    Q9NRR6
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