Integrin beta 3 antibody

Catalog No. ABIN7267928

The Rabbit Monoclonal anti-Integrin beta 3 antibody has been validated for WB, IHC and IP. It is suitable to detect Integrin beta 3 in samples from Human.

Quick Overview for Integrin beta 3 antibody (ABIN7267928)

Target: Integrin beta 3 (ITGB3)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Integrin beta 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-Integrin beta 3 Antibody

Purpose: Integrin beta 3 (ITGB3/CD61) Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Integrin beta 3 (ITGB3/CD61) (ITGB3/CD61)

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Integrin beta 3

Target: Integrin beta 3 (ITGB3)

Alternative Name: ITGB3

Background: The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008],BDPLT16,BDPLT2,CD61,GP3A,GPIIIa,GT,Integrin beta 3,ITGB3,Angiogenesis,Blood,Cancer,Cardiovascular,Cardiovascular diseases,Cardiovascular diseases_Hypertension,CDs,Cell Adhesion,Cell Biology & Developmental Biology,Cytoskeleton,G protein signaling,G protein signaling_G-Protein-Coupled Receptors Signaling to MAPK/Erk,Immunology & Inflammation,Invasion and Metastasis,MAPK-Erk Signaling Pathway,PI3K-Akt Signaling Pathway,Signal Transduction,ITGB3

Molecular Weight: 110kDa

Gene ID: 3690

UniProt: P05106

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex