IL11RA antibody

Catalog No. ABIN7267984

This Rabbit Monoclonal antibody specifically detects IL11RA in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for IL11RA antibody (ABIN7267984)

Target: IL11RA (Interleukin 11 Receptor, alpha (IL11RA))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IL11RA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-IL11RA Antibody

Purpose: IL11RA Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human IL11RA.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IL11RA

Target: IL11RA (Interleukin 11 Receptor, alpha (IL11RA))

Alternative Name: IL11RA

Background: Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene.,IL11RA, CRSDA, interleukin-11 receptor subunit alpha,Cancer,Tumor biomarkers,Immunology & Inflammation,Cytokines,Interleukins,Cell Intrinsic Innate Immunity Signaling Pathway,Stem Cells,Hematopoietic Progenitors,IL11RA

Molecular Weight: 45kDa

Gene ID: 3590

UniProt: Q14626

Pathways: JAK-STAT Signaling, Growth Factor Binding