KAT6B antibody (AA 400-500)

Catalog No. ABIN7268062

This Rabbit Polyclonal antibody specifically detects KAT6B in WB. It exhibits reactivity toward Human.

Quick Overview for KAT6B antibody (AA 400-500) (ABIN7268062)

Target: KAT6B (K(lysine) Acetyltransferase 6B (KAT6B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KAT6B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KAT6B Antibody

Binding Specificity: AA 400-500

Purpose: KAT6B Rabbit pAb

Sequence: DLDVFKQAQE LSWEKIECES GVEDCGRYPS VIEFGKYEIQ TWYSSPYPQE YARLPKLYLC EFCLKYMKSK NILLRHSKKC GWFHPPANEI YRRKDLSVFE V

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 400-500 of human KAT6B (NP_001243398.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KAT6B

Target: KAT6B (K(lysine) Acetyltransferase 6B (KAT6B))

Alternative Name: KAT6B

Background: The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene.,KAT6B,GTPTS,MORF,MOZ2,MYST4,ZC2HC6B,qkf,querkopf,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Acetylation,KAT6B

Gene ID: 23522

UniProt: Q8WYB5