KSR1 antibody (AA 320-420)

Catalog No. ABIN7268119

This Rabbit Polyclonal antibody specifically detects KSR1 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for KSR1 antibody (AA 320-420) (ABIN7268119)

Target: KSR1 (Kinase Suppressor of Ras 1 (KSR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KSR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-KSR1 Antibody

Binding Specificity: AA 320-420

Purpose: KSR1 Rabbit pAb

Sequence: SSPAPFPTSS NPSSATTPPN PSPGQRDSRF NFPAAYFIHH RQQFIFPVPS AGHCWKCLLI AESLKENAFN ISAFAHAAPL PEAADGTRLD DQPKADVLEA H

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 320-420 of human KSR1 (NP_055053.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KSR1

Target: KSR1 (Kinase Suppressor of Ras 1 (KSR1))

Alternative Name: KSR1

Background: Part of a multiprotein signaling complex which promotes phosphorylation of Raf family members and activation of downstream MAP kinases (By similarity. Independently of its kinase activity, acts as MAP2K1/MEK1 and MAP2K2/MEK2-dependent allosteric activator of BRAF, upon binding to MAP2K1/MEK1 or MAP2K2/MEK2, dimerizes with BRAF and promotes BRAF-mediated phosphorylation of MAP2K1/MEK1 and/or MAP2K2/MEK2. Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP (By similarity. Its kinase activity is unsure (By similarity. Some protein kinase activity has been detected in vitro, however the physiological relevance of this activity is unknown (By similarity.,KSR1,KSR,RSU2,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Serine/threonine kinases,Tyrosine kinases,MAPK-Erk Signaling Pathway,KSR1

Molecular Weight: 84kDa/87kDa/97kDa/102kDa

Gene ID: 8844

UniProt: Q8IVT5