LEFTY1 antibody (AA 77-366)

Catalog No. ABIN7268206

This Rabbit Polyclonal antibody specifically detects LEFTY1 in WB. It exhibits reactivity toward Human.

Quick Overview for LEFTY1 antibody (AA 77-366) (ABIN7268206)

Target: LEFTY1 (Left-Right Determination Factor 1 (LEFTY1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LEFTY1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LEFTY1 Antibody

Binding Specificity: AA 77-366

Purpose: LEFTY1 Rabbit pAb

Sequence: RFSQSFREVA GRFLALEAST HLLVFGMEQR LPPNSELVQA VLRLFQEPVP KAALHRHGRL SPRSARARVT VEWLRVRDDG SNRTSLIDSR LVSVHESGWK AFDVTEAVNF WQQLSRPRQP LLLQVSVQRE HLGPLASGAH KLVRFASQGA PAGLGEPQLE LHTLDLGDYG AQGDCDPEAP MTEGTRCCRQ EMYIDLQGMK WAENWVLEPP GFLAYECVGT CRQPPEALAF KWPFLGPRQC IASETDSLPM IVSIKEGGRT RPQVVSLPNM RVQKCSCASD GALVPRRLQP

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 77-366 of human LEFTY1 (NP_066277.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LEFTY1

Target: LEFTY1 (Left-Right Determination Factor 1 (LEFTY1))

Alternative Name: LEFTY1

Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. This gene is closely linked to both a related family member and a related pseudogene.,LEFTY1,LEFTB,LEFTYB,Cell Biology & Developmental Biology,Growth factor,Immunology & Inflammation,Cytokines,Stem Cells,LEFTY1

Molecular Weight: 40kDa

Gene ID: 10637

UniProt: O75610