LARS antibody (AA 1-270)

Catalog No. ABIN7268238

The Rabbit Polyclonal anti-LARS antibody (ABIN7268238) specifically detects LARS in WB and IF. The antibody is reactive with Human samples.

Quick Overview for LARS antibody (AA 1-270) (ABIN7268238)

Target: LARS (Leucyl-tRNA Synthetase (LARS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LARS antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-LARS Antibody

Binding Specificity: AA 1-270

Purpose: LARS Rabbit pAb

Sequence: MAERKGTAKV DFLKKIEKEI QQKWDTERVF EVNASNLEKQ TSKGKYFVTF PYPYMNGRLH LGHTFSLSKC EFAVGYQRLK GKCCLFPFGL HCTGMPIKAC ADKLKREIEL YGCPPDFPDE EEEEEETSVK TEDIIIKDKA KGKKSKAAAK AGSSKYQWGI MKSLGLSDEE IVKFSEAEHW LDYFPPLAIQ DLKRMGLKVD WRRSFITTDV NPYYDSFVRW QFLTLRERNK IKFGKRYTIY SPKDGQPCMD HDRQTGEGVG PQEYTLLKLK

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human LARS (NP_064502.9).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LARS

Target: LARS (Leucyl-tRNA Synthetase (LARS))

Alternative Name: LARS

Background: This gene encodes a cytosolic leucine-tRNA synthetase, a member of the class I aminoacyl-tRNA synthetase family. The encoded enzyme catalyzes the ATP-dependent ligation of L-leucine to tRNA(Leu). It is found in the cytoplasm as part of a multisynthetase complex and interacts with the arginine tRNA synthetase through its C-terminal domain. A mutation in this gene was found in affected individuals with infantile liver failure syndrome 1. Alternatively spliced transcript variants of this gene have been observed.,LARS,HSPC192,ILFS1,LARS1,LEURS,LEUS,LFIS,LRS,PIG44,RNTLS,hr025Cl,Epigenetics & Nuclear Signaling,Endocrine & Metabolism,Mitochondrial metabolism,LARS

Molecular Weight: 55kDa/128kDa/134kDa

Gene ID: 51520

UniProt: Q9P2J5

Pathways: EGFR Signaling Pathway