LIM Domain Binding 1 Protein antibody (AA 1-50)

Catalog No. ABIN7268255

The Rabbit Polyclonal anti-LIM Domain Binding 1 Protein antibody has been validated for WB and IHC. It is suitable to detect LIM Domain Binding 1 Protein in samples from Human.

Quick Overview for LIM Domain Binding 1 Protein antibody (AA 1-50) (ABIN7268255)

Target: LIM Domain Binding 1 Protein (LDB1) (LIM Domain Binding 1 (LDB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIM Domain Binding 1 Protein antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-LIM Domain Binding 1 Protein Antibody

Binding Specificity: AA 1-50

Purpose: LDB1 Rabbit pAb

Sequence: MLDRDVGPTP MYPPTYLEPG IGRHTPYGNQ TDYRIFELNK RLQNWTEECD

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-50 of human LDB1 (NP_003884.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LIM Domain Binding 1 Protein

Target: LIM Domain Binding 1 Protein (LDB1) (LIM Domain Binding 1 (LDB1))

Alternative Name: LDB1

Background: Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity.,CLIM-2,CLIM2,LDB-1,NLI,LDB1,Epigenetics & Nuclear Signaling,Neuroscience,LDB1

Gene ID: 8861

UniProt: Q86U70

Pathways: Stem Cell Maintenance, Chromatin Binding