Lipin 1 antibody

Catalog No. ABIN7268281

This Rabbit Monoclonal antibody specifically detects Lipin 1 in WB. It exhibits reactivity toward Human.

Quick Overview for Lipin 1 antibody (ABIN7268281)

Target: Lipin 1 (LPIN1)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Lipin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Lipin 1 Antibody

Purpose: Lipin 1 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Lipin 1

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Lipin 1

Target: Lipin 1 (LPIN1)

Alternative Name: LPIN1

Background: This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, acute recurrent rhabdomyolysis, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. [provided by RefSeq, Mar 2017],PAP1,Cardiovascular,Cardiovascular diseases,Cardiovascular diseases_Heart disease,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cell differentiation,Endocrine & Metabolism,Endocrine and metabolic diseases,Endocrine and metabolic diseases_Diabetes,Heart,Lipid Metabolism,Lipid Metabolism_Cholesterol Metabolism,Lipids,Signal Transduction,LPIN1

Molecular Weight: 130kDa

Gene ID: 23175

UniProt: Q14693

Pathways: Monocarboxylic Acid Catabolic Process