LONP2 antibody (AA 1-300)

Catalog No. ABIN7268293

This Rabbit Polyclonal antibody specifically detects LONP2 in WB. It exhibits reactivity toward Human.

Quick Overview for LONP2 antibody (AA 1-300) (ABIN7268293)

Target: LONP2 (Lon Peptidase 2, Peroxisomal (LONP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LONP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LONP2 Antibody

Binding Specificity: AA 1-300

Purpose: LONP2 Rabbit pAb

Sequence: MSSVSPIQIP SRLPLLLTHE GVLLPGSTMR TSVDSARNLQ LVRSRLLKGT SLQSTILGVI PNTPDPASDA QDLPPLHRIG TAALAVQVVG SNWPKPHYTL LITGLCRFQI VQVLKEKPYP IAEVEQLDRL EEFPNTCKMR EELGELSEQF YKYAVQLVEM LDMSVPAVAK LRRLLDSLPR EALPDILTSI IRTSNKEKLQ ILDAVSLEER FKMTIPLLVR QIEGLKLLQK TRKPKQDDDK RVIAIRPIRR ITHISGTLED EDEDEDNDDI VMLEKKIRTS SMPEQAHKVC VKEIKRLKKM

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human LONP2 (NP_113678.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LONP2

Target: LONP2 (Lon Peptidase 2, Peroxisomal (LONP2))

Alternative Name: LONP2

Background: In human, peroxisomes function primarily to catalyze fatty acid beta-oxidation and, as a by-product, produce hydrogen peroxide and superoxide. The protein encoded by this gene is an ATP-dependent protease that likely plays a role in maintaining overall peroxisome homeostasis as well as proteolytically degrading peroxisomal proteins damaged by oxidation. The protein has an N-terminal Lon N substrate recognition domain, an ATPase domain, a proteolytic domain, and, in some isoforms, a C-terminal peroxisome targeting sequence. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,LONP2,LONP,LONPL,PLON,PSLON,Cell Biology & Developmental Biology,Ubiquitin,LONP2

Molecular Weight: 89kDa/94kDa

Gene ID: 83752

UniProt: Q86WA8