MANBA antibody (AA 18-300)

Catalog No. ABIN7268392

This Rabbit Polyclonal antibody specifically detects MANBA in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for MANBA antibody (AA 18-300) (ABIN7268392)

Target: MANBA (Mannosidase, beta A, Lysosomal (MANBA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MANBA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MANBA Antibody

Binding Specificity: AA 18-300

Purpose: MANBA Rabbit pAb

Sequence: AAELSYSLRG NWSICNGNGS LELPGAVPGC VHSALFQQGL IQDSYYRFND LNYRWVSLDN WTYSKEFKIP FEISKWQKVN LILEGVDTVS KILFNEVTIG ETDNMFNRYS FDITNVVRDV NSIELRFQSA VLYAAQQSKA HTRYQVPPDC PPLVQKGECH VNFVRKEQCS FSWDWGPSFP TQGIWKDVRI EAYNICHLNY FTFSPIYDKS AQEWNLEIES TFDVVSSKPV GGQVIVAIPK LQTQQTYSIE LQPGKRIVEL FVNISKNITV ETWWPHGHGN QTG

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 18-300 of human MANBA (NP_005899.3).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MANBA

Target: MANBA (Mannosidase, beta A, Lysosomal (MANBA))

Alternative Name: MANBA

Background: This gene encodes a member of the glycosyl hydrolase 2 family. The encoded protein localizes to the lysosome where it is the final exoglycosidase in the pathway for N-linked glycoprotein oligosaccharide catabolism. Mutations in this gene are associated with beta-mannosidosis, a lysosomal storage disease that has a wide spectrum of neurological involvement.,MANBA,MANB1,Cancer,Signal Transduction,Endocrine & Metabolism,Neuroscience,MANBA

Molecular Weight: 100kDa

Gene ID: 4126

UniProt: O00462