MTIF2 antibody (AA 428-727)

Catalog No. ABIN7268591

The Rabbit Polyclonal anti-MTIF2 antibody has been validated for WB, IHC and IF. It is suitable to detect MTIF2 in samples from Human.

Quick Overview for MTIF2 antibody (AA 428-727) (ABIN7268591)

Target: MTIF2 (Mitochondrial Translational Initiation Factor 2 (MTIF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTIF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MTIF2 Antibody

Binding Specificity: AA 428-727

Purpose: MTIF2 Rabbit pAb

Sequence: GEEILEVESE PRAREVVDWR KYEQEQEKGQ EDLKIIEEKR KEHKEAHQKA REKYGHLLWK KRSILRFLER KEQIPLKPKE KRERDSNVLS VIIKGDVDGS VEAILNIIDT YDASHECELE LVHFGVGDVS ANDVNLAETF DGVIYGFNVN AGNVIQQSAA KKGVKIKLHK IIYRLVEDLQ EELSSRLPCA VEEHPVGEAS ILATFSVTEG KKKVPVAGCR VQKGQLEKQK KFKLTRNGHV IWKGSLTSLK HHKDDISIVK TGMDCGLSLD EDNMEFQVGD RIVCYEEKQI QAKTSWDPGF

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 428-727 of human MTIF2 (NP_002444.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MTIF2

Target: MTIF2 (Mitochondrial Translational Initiation Factor 2 (MTIF2))

Alternative Name: MTIF2

Background: During the initiation of protein biosynthesis, initiation factor-2 (IF-2) promotes the binding of the initiator tRNA to the small subunit of the ribosome in a GTP-dependent manner. Prokaryotic IF-2 is a single polypeptide, while eukaryotic cytoplasmic IF-2 (eIF-2) is a trimeric protein. Bovine liver mitochondria contain IF-2(mt), an 85-kD monomeric protein that is equivalent to prokaryotic IF-2. The predicted 727-amino acid human protein contains a 29-amino acid presequence. Human IF-2(mt) shares 32 to 38 % amino acid sequence identity with yeast IF-2(mt) and several prokaryotic IF-2s, with the greatest degree of conservation in the G domains of the proteins.,MTIF2,Epigenetics & Nuclear Signaling,RNA Binding,Endocrine & Metabolism,Mitochondrial metabolism,MTIF2

Molecular Weight: 81kDa

Gene ID: 4528

UniProt: P46199

Pathways: Ribonucleoprotein Complex Subunit Organization