ALKBH8 antibody (AA 245-350)

Catalog No. ABIN717356

The Rabbit Polyclonal anti-ALKBH8 antibody has been validated for ELISA, IF (cc), IF (p), IHC (p) and IHC (fro). It is suitable to detect ALKBH8 in samples from Rat.

Quick Overview for ALKBH8 antibody (AA 245-350) (ABIN717356)

Target: ALKBH8 (AlkB, Alkylation Repair Homolog 8 (ALKBH8))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALKBH8 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ALKBH8 Antibody

Binding Specificity: AA 245-350

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ABH8/ALKBH8

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ALKBH8

Target: ALKBH8 (AlkB, Alkylation Repair Homolog 8 (ALKBH8))

Alternative Name: ABH8

Background:

Synonyms: ABH8, alkB alkylation repair homolog 8 E. coli, alkB alkylation repair homolog 8, AlkB homologue 8, ALKB8_HUMAN, ALKBH8, Alkylated DNA repair protein alkB homolog 8, Probable alpha-ketoglutarate-dependent dioxygenase ABH8, S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8.

Background: Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis.

Gene ID: 91801