MBNL1 antibody

Catalog No. ABIN7268704

This Rabbit Monoclonal antibody specifically detects MBNL1 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for MBNL1 antibody (ABIN7268704)

Target: MBNL1 (Muscleblind-like Protein 1 (MBNL1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MBNL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-MBNL1 Antibody

Purpose: MBNL1 Rabbit mAb

Cross-Reactivity: Human

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human MBNL1

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MBNL1

Target: MBNL1 (Muscleblind-like Protein 1 (MBNL1))

Alternative Name: MBNL1

Background: This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities. [provided by RefSeq, Sep 2015],EXP, MBNL,Epigenetics & Nuclear Signaling,RNA Binding,MBNL1

Molecular Weight: 40kDa

Gene ID: 4154

UniProt: Q9NR56

Pathways: Ribonucleoprotein Complex Subunit Organization