ALKBH8 antibody (AA 245-350) (FITC)

Catalog No. ABIN717363

This anti-ALKBH8 antibody is a Rabbit Polyclonal antibody detecting ALKBH8 in IF (cc) and IF (p). Suitable for Rat.

Quick Overview for ALKBH8 antibody (AA 245-350) (FITC) (ABIN717363)

Target: ALKBH8 (AlkB, Alkylation Repair Homolog 8 (ALKBH8))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALKBH8 antibody is conjugated to FITC

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-ALKBH8 Antibody (FITC)

Binding Specificity: AA 245-350

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ABH8/ALKBH8

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ALKBH8

Target: ALKBH8 (AlkB, Alkylation Repair Homolog 8 (ALKBH8))

Alternative Name: ABH8

Background:

Synonyms: ABH8, alkB alkylation repair homolog 8 E. coli, alkB alkylation repair homolog 8, AlkB homologue 8, ALKB8_HUMAN, ALKBH8, Alkylated DNA repair protein alkB homolog 8, Probable alpha-ketoglutarate-dependent dioxygenase ABH8, S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8.

Background: Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis.

Gene ID: 91801